Take control of your process with the CTech™ FlowVPX® System. The in-line Slope Spectroscopy® method enables users to monitor and optimize critical process parameters and make real time decisions for enhanced biologic product consistency and quality. Eliminate off-line measurements, out-of-spec results, and costly and time-consuming deviation reports by incorporating the FlowVPX System as part of your process analytical technology (PAT) strategy. In-line concentration measurements using the slope-based method, increases the efficiency of your process and avoids costly dilution and background correction steps.
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Capable of making spectral and fixed-point measurements at wavelengths between 190 nm and 1100 nm using variable pathlength technology, the FlowVPX System is adaptable to a wide range of sample types and the highest concentrations found in the biopharmaceutical industry. It can support lab-scale flow lines of 3 mm, pilot-scale flow lines of 10 mm, and production-scale flow lines of 22 mm. These processes include UF/DF, chromatography, mixing, and fill finish.
Directly incorporating the FlowVPX System into one or more locations of a process stream helps to reveal process characteristics previously hidden from commonly used online fixed pathlength sensors. The versatility of this robust inprocess technology is unparalleled, helping you expedite process development and manufacturing time.
Increase process understanding in process development stage to accelerate product to market
Reduce cycling time and increase process efficiency (yield, throughput, resource utilization) by eliminating delays associated with off-line testing
Strengthen your process control with high quality and highly reproducible results
Minimize risk with continuous monitoring throughout the process
316L stainless steel body is designed to be fully enclosed to withstand the harshest GMP manufacturing environments. Passed IP65, C1D2, CE marking.
ViPER™ Anlytx software platform enables SecureVPT settings for 21 CFR Part 11 and Annex 11 compliance.
Modular component design allows for increased scalability from development to laboratory to production with three different removable Flow Cell options:
3 mm Flow Cell volume: 0.6 mL
10 mm Flow Cell volume: 9.0 mL
22 mm Flow Cell volume: 46.0 mL
Process connectivity via barb, Luer, and compression fittings (included).
Designed with three digital input channels, three digital output channels, and two analog output channels to allow for seamless integration.
Ensures accurate zeroing and prevents window breakage.
The FlowVPX System automatically identifies the linear region of the section data sets to verify the compliance with Beer-Lambert law.
On-site installation and training included with System purchase.
Operating System: Windows 10 compatible
Software Environment: ViPER™ v1.0.0 and Agilent WinUV Software Suite v5.1.0.1019 or newer
Required Computer Hardware: Repligen recommends:
Support Services
Enjoy the benefit of year-round discounts and support. We offer one to three year service contracts for your SoloVPE System. Schedule a visit from a Repligen Analytics Representative to qualify your SoloVPE System.
Application Services
Supplementary to our standard support options, application services provide you with increased access to our highly knowledgeable and experienced professionals. We offer implementation, development, and educational guidance to maximize the benefits of your variable pathlength solutions and the Slope Spectroscopy® technique.
| Product Feature |
FlowVPE View Product
|
FlowVPX View Product
|
|---|---|---|
| Data Collection | At-line process analytics | In-line process monitoring |
| Inline UV-Measurement | ||
| System Suitability Testing Capability | ||
| Minimum 5-Second Cycle Acquisition Time | ||
| CE System Certification | ||
| ViPER™ Software Compatibility | ||
| 21 CFR Part 11 Compliance | ||
| Analog I/O | ||
| Digital I/O | ||
| Automated Zeroing | ||
| Smart Cell Operation | ||
| Process Status Indicators | ||
| C1D2 Rating | ||
| IP Rating | N/A | IP65 |
| Concentration Range | 0.1–250 mg/mL | 0.1–300 mg/mL |
| Flow Cell Size Compatibility | Up to 22 mm | Increase scalability |
| Minimum Pathlength Step Size | 5 µm | 1 µm |
| Contact a Specialist | Contact a Specialist |
685 Route 202/206
Bridgewater, NJ 08807 US
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