Application of In-Line Variable Pathlength CTech FlowVPX System for Use of Concentration as a Feedback Loop

Development of effective, commercially-viable process analytical technology tools requires the interconnection of processing equipment and analytical tools with robust methods and reliable controls. The objective of this study was to create a fully automated TFF process solely based on concentration and compare it to the traditional TFF process which is based on the weight of the balances. The FlowVPX System can be used in-line as a process to provide concentration data in real time to be used as a feedback loop to control the process instead of using balances.