Watch our expert webinar series where 4 different industry experts will share how they implemented in-line variable pathlength spectroscopy into their PAT strategy. Topics include in-line VPT implementation in batch/continuous chromatography, UF/DF process in drug substance manufacturing, and automation of the dilution process during formulation in fill-finish manufacturing.
Explore these resources for a deeper dive into the science behind Slope Spectroscopy and Variable Pathlength Technology.
Learn more about the success and advantages of Variable Pathlength Technology within the laboratory settings of some of our customers, including Ionis, Amgen, Bristol-Myers Squibb, and more.
Find out how our customers, like Amgen, Biogen, Genentech, and more, use Slope Spectroscopy and Variable Pathlength Technology in their work.
See the FlowVPX® System in action with the Repligen KR2i TFF system to monitor and control UFDF by concentration, not weight. The FlowVPX system allows in-line process analytics (PAT) which complements the KR2i and larger-scale TFF systems. Rather than using UV sensors simply to monitor filter integrity, the FlowVPX can measure real-time concentration in the retentate line and control the entire process by connecting with the KR2i. Many target analytes can be quantitated – mRNA, DNA, proteins, peptides, ADCs, viral vectors, LNPs, exosomes, and more.
Browser our webinars and learn the power of our devices in various applications.
In this webinar, we will demonstrate how the CTech SoloVPE System, when used at-line in one or more stages of a process, can help to quickly identify process characteristics, provide key insights and allow for process optimization in minutes. VPT has enabled at-line measurement of concentration by eliminating the need for sample dilution or manipulation and delivering rapid and highly accurate real-time results.
In this webinar, we will share multiple applications and technologies that can address current manufacturing challenges and solutions to increase overall viral vector yield in various stages throughout the development and manufacturing processes. We will begin with strategies for intensifying plasmid DNA production, to secure the demand and quality of the raw material for AAV production. We will also discuss strategies to overcome the pain points associated with AAV and lentivirus production and purification at various manufacturing scales.
In this webinar, we will demonstrate a practical business case where Slope Spectroscopy can save laboratory time and reagent/consumable cost, maximize FTE resources, eliminate unnecessary repeats and documentation, reduce batch-failures and deviations, and shorten the process development to market.
This webinar will share Regeneron’s experience with implementing the SoloVPE® technology in the Quality Control laboratories. It will describe the company’s use of the technology for protein concentration measurement of monoclonal antibodies, the benefits compared to previous protein concentration methods, and the challenges faced during implementation and validation.
In this webinar we will demonstrate how the FlowVPE Slope Spectroscopy System, when directly integrated in one or more locations of a process stream, has helped reveal process characteristics that until now have been hidden due to the limitations of the most commonly used online fixed pathlength UV-Vis solutions.
In this webinar, we will review VPT and how it can be used in various applications from protein therapeutics to gene therapy. We will share real-world case studies demonstrating how leading biologic companies have integrated the SoloVPE System into their manufacturing workflow for release and in-process testing.
Process Analytical Technology (PAT) is intended to support innovation and efficiency in biological therapeutics development, manufacturing, and quality assurance. In-line or near-line measurements of product purity are particularly important to improve efficiencies, reduce risk and improve product quality. The application of variable pathlength (VP) UV spectroscopy allows for concentration measurements in an extended dynamic range. Join us to learn from the experts that have successfully implemented variable pathlength technology into their PAT strategies.
Process monitoring and control are of the highest importance in the manufacturing of such microorganisms to allow good product quality when monitoring the growth kinetics of the cells. Learn how CTech™ SoloVPE® System’s variable pathlength technology can adapt optical density measurements as an in-line or at-line monitoring tool for cell growth in bioreactors.
Watch the CTech SoloVPE System in action. Learn best practices, how to support and maintain your instrument.
Our latest technology, the CTech FlowVPX System will optimize your process. Learn best practices, how to support and maintain your instrument.
Learn how to load and unload the Flow Cell for your CTech FlowVPE System.
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